Swine Flu

rockvocalist_76
By rockvocalist_76

As Received [FYI]
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What is swine flu?

- Swine flu is a type A influenza virus present in pigs. Human infection is usually uncommon except among people who work and live closely with pigs.

What is unusual about the present strain?

- The new strain is a hybrid of swine, human and avian flu viruses and the US Centers for Disease Control and Prevention (CDC) says it can spread from human to human but the level of virulence is not yet clear.

What are the symptoms?

- Symptoms are similar to regular human flu: fever and chills, a cough, sore throat, aching limbs, headaches, and general malaise. However, there are reports of swine flu also causing diarrhoea and vomiting. Pneumonia and respiratory failure can occur leading to death as also happens in regular human flu, which kills thousands of people every year.

Are there warning signs in children?

- Children having trouble breathing, being averse to drinking, lethargy not waking up or not interacting, being so irritable that the child does not want to beheld, flu-like symptoms improve but then return with fever and worse cough, fever with a rash.

Are there any drugs to treat swine flu?

- Oseltamivir (Tamiflu) and zanamivir (Relenza) are the possible pharmaceutical frontline defence and are proving effective in treating patients diagnosed early enough. There is no vaccine.

How can we prevent the spread of swine flu?

- People at risk should cover their mouth when they cough. They should regularly wash their hands with an alcohol-based cleaner and and avoid close contact with the sick. Patients with the disease should stay at home.

Will there be a global flu epidemic?

- “We do not know whether this swine flu virus or some other influenza virus will lead to the next pandemic,” says, Richard Besser, acting director of the CDC, “However, scientists around the world continue to monitor the virus and take its threat seriously.”

Swine flu could be the next major disease epidemic. It appears to have emerged in Mexico has killed more than 100 people and infected more 1000 who have recovered. Cases and suspected cases have now been identified in the USA, New Zealand, France, Scotland, Israel, Spain, and elsewhere (see the swine flu outbreak Google Map).

How many people infected?

- Cases in Mexico number around 1600, according to Mexican Health Secretary Jose Angel Cordova.

Is this swine flu the same strain of flu that killed millions in 1918, the so-called Spanish flu?

- No. The present strain is a type A influenza virus of class H1N1, certainly, but it is a different sub-species. Influenza viruses evolve very rapidly in response to changes in the immune systems of their hosts.

What does H1N1 mean?

- The “H” refers to the viral hem agglutinin protein, and the “N” refers to the neuraminidase protein (enzyme). There are H1N2, H3N1, H3N2, and H2N3 strains of swine flu endemic in pig populations.

Whatever happened to bird flu?
- Strains of avian influenza, or bird flu, are still around, these viruses exist in host species in Asia and potentially elsewhere and could still make the leap to humans at any time.

Why pigs?

- Influenza viruses can exist endemically in pigs as well as birds and other species. The current strain of interest, swine flu, is endemic in pig populations in Mexico but has now spread to people.

Didn’t we have swine flu before?

- Swine flu has been present for years and commonly infects people who work with pigs. An outbreak at the Fort Dix army base killed and hospitalized soldiers there and led to an ill-fated mass-vaccination campaign under President Ford. An outbreak of swine flu happened in the Philippines in 2007.

Was the new swine flu genetically engineered as a bioweapon?

- It is perhaps possible to engineer a virus, but the precursors to this present strain of influenza has been seen in the wild for years and so it would seem highly unlikely that it was synthesized. Is there a lab that could synthesize a whole new viable viral species from combined segments of human, bird, and pig influenza viruses?

But how did porcine, avian, and human viruses get mixed together?

- These flu viruses have a segmented genome containing eight pieces of RNA. If two strains infect a single cell their progeny undergo reassortment so that new strains emerge. Pigs are a particularly good biological mixing bowl for flu viruses, it takes just one lucky reassortment that can infect humans to then make the species leap. This has happened several times in the past.

What is WHO doing about the outbreak?

- The World Health Organisation will meet in Geneva on Tuesday (April 28) to discuss whether to raise the pandemic alert level.

Source: Science Base/ Sci-Tec news & views

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