We had a problem with our daughter biting to the point her teeth marks the whole mouth were on my son.  The Pediatrician told us to let him bite her back and sure enough it only takes once and they learn.  Same with manipulation she would throw up in her bed to get out and I would take her out and clean the bed the dr. told me to leave her in it one night and she won't do it again, it worked as well.  Sounds harsh but people bites are dangerous.